Publications

Scholarly Journals--Published

  • Bhise V, Waltz M, Casper TC, Aaen G, Benson L, Chitnis T, Gorman M, Goyal MS, Wheeler Y, Lotze T, Mar S, Rensel M, Abrams A, Rodriguez M, Rose J, Schreiner T, Shukla N, Waubant E, Weinstock-Guttman B, Ness J, Krupp L, Mendelt-Tillema J; U.S. Network of Pediatric Multiple Sclerosis Centers. Silent findings: Examination of asymptomatic demyelination in a pediatric US cohort. Mult Scler Relat Disord. 2023 Mar;71:104573. doi: 10.1016/j.msard.2023.104573. Epub 2023 Feb 18. PMID: 36871372. (03/2023) (link)
  • Nasr Z, Schoeps VA, Ziaei A, Virupakshaiah A, Adams C, Casper TC, Waltz M, Rose J, Rodriguez M, Tillema JM, Chitnis T, Graves JS, Benson L, Rensel M, Krupp L, Waldman AT, Weinstock-Guttman B, Lotze T, Greenberg B, Aaen G, Mar S, Schreiner T, Hart J, Simpson-Yap S, Mesaros C, Barcellos LF, Waubant E. Gene-environment interactions increase the risk of paediatric-onset multiple sclerosis associated with household chemical exposures. J Neurol Neurosurg Psychiatry. 2023 Feb 1:jnnp-2022-330713. doi: 10.1136/jnnp-2022-330713. Epub ahead of print. PMID: 36725329. (02/2023) (link)
  • Horton MK, Shim JE, Wallace A, Graves JS, Aaen G, Greenberg B, Mar S, Wheeler Y, Weinstock-Guttman B, Waldman A, Schreiner T, Rodriguez M, Tillema JM, Chitnis T, Krupp L, Casper TC, Rensel M, Hart J, Quach HL, Quach DL, Schaefer C, Waubant E, Barcellos LF. Rare and low-frequency coding genetic variants contribute to pediatric-onset multiple sclerosis. Mult Scler. 2023 Feb 8:13524585221150736. doi: 10.1177/13524585221150736. Epub ahead of print. PMID: 36755464. (02/2023) (link)
  • Pizzolato Umeton R, Waltz M, Aaen GS, Benson L, Gorman M, Goyal M, Graves JS, Harris Y, Krupp L, Lotze TE, Shukla NM, Mar S, Ness J, Rensel M, Schreiner T, Tillema JM, Roalstad S, Rodriguez M, Rose J, Waubant E, Weinstock-Guttman B, Casper C, Chitnis T; US Network of Pediatric MS Centers. Therapeutic Response in Pediatric Neuromyelitis Optica Spectrum Disorder. Neurology. 2023 Feb 28;100(9):e985-e994. doi: 10.1212/WNL.0000000000201625. Epub 2022 Dec 2. PMID: 36460473; PMCID: PMC9990442. (02/2023) (link)
  • Gaudioso CM, Mar S, Casper TC, Codden R, Nguyen A, Aaen G, Benson L, Chitnis T, Francisco C, Gorman MP, Goyal MS, Graves J, Greenberg BM, Hart J, Krupp L, Lotze T, Narula S, Pittock SJ, Rensel M, Rodriguez M, Rose J, Schreiner T, Tillema JM, Waldman A, Weinstock-Guttman B, Wheeler Y, Waubant E, Flanagan EP; United States Network of Pediatric Multiple Sclerosis Centers. MOG and AQP4 Antibodies among Children with Multiple Sclerosis and Controls. Ann Neurol. 2023 Feb;93(2):271-284. doi: 10.1002/ana.26502. Epub 2022 Oct 4. PMID: 36088544. (02/2023) (link)
  • Krupp LB, Waubant E, Waltz M, Casper TC, Belman A, Wheeler Y, Ness J, Graves J, Gorman M, Benson L, Mar S, Goyal M, Schreiner T, Weinstock-Guttman B, Rodriguez M, Tillema JM, Lotze T, Aaen G, Rensel M, Rose J, Chitinis T, George A, Charvet LE; US Network of Pediatric MS Centers. A new look at cognitive functioning in pediatric MS. Mult Scler. 2023 Jan;29(1):140-149. doi: 10.1177/13524585221123978. Epub 2022 Oct 1. PMID: 36189711. (01/2023) (link)
  • Ziaei A, Lavery AM, Shao XM, Adams C, Casper TC, Rose J, Candee M, Weinstock-Guttman B, Aaen G, Harris Y, Graves J, Benson L, Gorman M, Rensel M, Mar S, Lotze T, Greenberg B, Chitnis T, Hart J, Waldman AT, Barcellos LF, Waubant E. Gene-environment interactions increase the risk of pediatric-onset multiple sclerosis associated with ozone pollution. Mult Scler. 2022 Aug;28(9):1330-1339. doi: 10.1177/13524585211069926. Epub 2022 Jan 8.PMID: 35000467  (08/2022) (link)
  • Sebastian P, Cherbuin N, Barcellos LF, Roalstad S, Casper C, Hart J, Aaen GS, Krupp L, Benson L, Gorman M, Candee M, Chitnis T, Goyal M, Greenberg B, Mar S, Rodriguez M, Rubin J, Schreiner T, Waldman A, Weinstock-Guttman B, Graves J, Waubant E, Lucas R; US Network of Pediatric Multiple Sclerosis Centers. Association Between Time Spent Outdoors and Risk of Multiple Sclerosis. Neurology. 2021 Dec 8:10.1212/WNL.0000000000013045. doi: 10.1212/WNL.0000000000013045.  (12/2021) (link)
  • Greenberg BM, Casper TC, Mar SS, Ness JM, Plumb P, Liang S, Goyal M, Weinstock-Guttman B, Rodriguez M, Aaen GS, Belman A, Barcellos LF, Rose JW, Gorman MP, Benson LA, Candee M, Chitnis T, Harris YC, Kahn IL, Roalstad S, Hart J, Lotze TE, Rensel M, Rubin JP, Schreiner TL, Tillema JM, Waldman AT, Krupp L, Graves J, Drake K, Waubant E. Familial History of Autoimmune Disorders Among Patients With Pediatric Multiple Sclerosis. Neurol Neuroimmunol Neuroinflamm. 2021 Aug 5;8(5):e1049. doi: 10.1212/NXI.0000000000001049. Print 2021 Sep.PMID: 34353894 (08/2021) (link)
  • Alroughani R, Huppke P, Mazurkiewicz-Beldzinska M, Blaschek A, Valis M, Aaen G, Pultz J, Peng X, Beynon V. Delayed-Release Dimethyl Fumarate Safety and Efficacy in Pediatric Patients With Relapsing-Remitting Multiple Sclerosis. Front Neurol. 2021 Jan 4;11:606418. doi: 10.3389/fneur.2020.606418. eCollection 2020. (01/2021) (link)
  • Krysko KM, Graves JS, Rensel M, Weinstock-Guttman B, Rutatangwa A, Aaen G, Belman A, Benson L, Chitnis T, Gorman M, Goyal MS, Harris Y, Krupp L, Lotze T, Mar S, Moodley M, Ness J, Rodriguez M, Rose J, Schreiner T, Tillema JM, Waltz M, Casper TC, Waubant E; US Network of Pediatric MS Centers. Real-World Effectiveness of Initial Disease-Modifying Therapies in Pediatric Multiple Sclerosis. Ann Neurol. 2020;88(1):42-55. doi:10.1002/ana.25737 (07/2020) (link)
  • Wallach AI, Waltz M, Casper TC, Aaen G, Belman A, Benson L, Chitnis T, Gorman M, Graves J, Harris Y, Lotze TE, Mar S, Moodley M, Ness JM, Rensel M, Rodriguez M, Rose JW, Schreiner T, Tillema JM, Waubant E, Weinstock-Guttman B, Charvet LE, Krupp LB. Cognitive processing speed in pediatric-onset multiple sclerosis: Baseline characteristics of impairment and prediction of decline [published online ahead of print, 2019 Nov 28]. Mult Scler. 2019;1352458519891984. doi:10.1177/1352458519891984 (11/2019) (link)
  • Graves JS, Barcellos LF, Krupp L, Belman A, Shao X, Quach H, Hart J, Chitnis T, Weinstock-Guttman B, Aaen G, Benson L, Gorman M, Greenberg B, Lotze T, Soe M, Ness J, Rodriguez M, Rose J, Schreiner T, Tillema JM, Waldman A, Casper TC, Waubant E. Vitamin D genes influence MS relapses in children [published online ahead of print, 2019 May 13]. Mult Scler. 2019;1352458519845842. doi:10.1177/1352458519845842 (05/2019) (link)
  • Rhead B, Shao X, Graves JS, Chitnis T, Waldman AT, Lotze T, Schreiner T, Belman A, Krupp L, Greenberg BM, Weinstock-Guttman B, Aaen G, Tillema JM, Rodriguez M, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee MS, Gorman M, Benson L, Mar S, Kahn I, Rose J, Casper TC, Quach H, Quach D, Schaefer C, Waubant E, Barcellos LF; US Network of Pediatric MS Centers. miRNA contributions to pediatric-onset multiple sclerosis inferred from GWAS. Ann Clin Transl Neurol. 2019;6(6):1053-1061. Published 2019 May 15. doi:10.1002/acn3.786 (05/2019) (link)
  • Aaen G, Waltz M, Vargas W, Makhani N, Ness J, Harris Y, Casper TC, Benson L, Candee M, Chitnis T, Gorman M, Graves J, Greenberg B, Lotze T, Mar S, Tillema JM, Rensel M, Rodriguez M, Rose J, Rubin J, Schreiner T, Waldman A, Weinstock-Guttman B, Belman A, Waubant E, Krupp L. Acquisition of Early Developmental Milestones and Need for Special Education Services in Pediatric Multiple Sclerosis. J Child Neurol. 2019;34(3):148-152. doi:10.1177/0883073818815041 (03/2019) (link)
  • Chi C, Shao X, Rhead B, Gonzales E, Smith JB, Xiang AH, Graves J, Waldman A, Lotze T, Schreiner T, Weinstock-Guttman B, Aaen G, Tillema JM, Ness J, Candee M, Krupp L, Gorman M, Benson L, Chitnis T, Mar S, Belman A, Casper TC, Rose J, Moodley M, Rensel M, Rodriguez M, Greenberg B, Kahn L, Rubin J, Schaefer C, Waubant E, Langer-Gould A, Barcellos LF. Admixture mapping reveals evidence of differential multiple sclerosis risk by genetic ancestry. PLoS Genet. 2019;15(1):e1007808. Published 2019 Jan 17. doi:10.1371/journal.pgen.1007808 (01/2019) (link)
  • Gianfrancesco MA, Stridh P, Shao X, Rhead B, Graves JS, Chitnis T, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Mar S, Kahn I, Rose J, Roalstad S, Casper TC, Shen L, Quach H, Quach D, Hillert J, Hedstrom A, Olsson T, Kockum I, Alfredsson L, Schaefer C, Barcellos LF, Waubant E; Network of Pediatric Multiple Sclerosis Centers. Genetic risk factors for pediatric-onset multiple sclerosis. Mult Scler. 2018;24(14):1825-1834. doi:10.1177/1352458517733551 (12/2018) (link)
  • Krysko KM, Graves J, Rensel M, Weinstock-Guttman B, Aaen G, Benson L, Chitnis T, Gorman M, Goyal M, Krupp L, Lotze T, Mar S, Rodriguez M, Rose J, Waltz M, Charles Casper T, Waubant E; US Network of Pediatric MS Centers. Use of newer disease-modifying therapies in pediatric multiple sclerosis in the US. Neurology. 2018;91(19):e1778-e1787. doi:10.1212/WNL.0000000000006471 (11/2018) (link)
  • Mar S, Liang S, Waltz M, Casper TC, Goyal M, Greenberg B, Weinstock-Guttman B, Rodriguez M, Aaen G, Belman A, Barcellos LF, Rose J, Gorman M, Benson L, Candee M, Chitnis T, Harris Y, Kahn I, Roalsted S, Hart J, Lotze T, Moodley M, Ness J, Rensel M, Rubin J, Schreiner T, Tillema JM, Waldman A, Krupp L, Graves JS, Waubant E; U.S. Network of Pediatric Multiple Sclerosis Centers. Several household chemical exposures are associated with pediatric-onset multiple sclerosis. Ann Clin Transl Neurol. 2018;5(12):1513-1521. Published 2018 Oct 9. doi:10.1002/acn3.663 (10/2018) (link)
  • Lavery AM, Waubant E, Casper TC, Roalstad S, Candee M, Rose J, Belman A, Weinstock-Guttman B, Aaen G, Tillema JM, Rodriguez M, Ness J, Harris Y, Graves J, Krupp L, Charvet L, Benson L, Gorman M, Moodley M, Rensel M, Goyal M, Mar S, Chitnis T, Schreiner T, Lotze T, Greenberg B, Kahn I, Rubin J, Waldman AT. Urban air quality and associations with pediatric multiple sclerosis. Ann Clin Transl Neurol. 2018;5(10):1146-1153. Published 2018 Sep 27. doi:10.1002/acn3.616 (09/2018) (link)
  • López-Chiriboga AS, Klein C, Zekeridou A, McKeon A, Dubey D, Flanagan EP, Lennon VA, Tillema JM, Wirrell EC, Patterson MC, Gadoth A, Aaen G, Brenton JN, Bui JD, Moen A, Otten C, Piquet A, Pittock SJ. LGI1 and CASPR2 neurological autoimmunity in children. Ann Neurol. 2018;84(3):473-480. doi:10.1002/ana.25310 (09/2018) (link)
  • Nourbakhsh B, Rutatangwa A, Waltz M, Rensel M, Moodley M, Graves J, Casper TC, Waldman A, Belman A, Greenberg B, Goyal M, Harris Y, Kahn I, Lotze T, Mar S, Schreiner T, Aaen G, Hart J, Ness J, Rubin J, Tillema JM, Krupp L, Gorman M, Benson L, Rodriguez M, Chitnis T, Rose J, Candee M, Weinstock-Guttman B, Shao X, Barcellos L, James J, Waubant E; US Network of Pediatric MS Centers. Heterogeneity in association of remote herpesvirus infections and pediatric MS. Ann Clin Transl Neurol. 2018 Sep 17;5(10):1222-1228. (09/2018) (link)
  • Suleiman L, Waubant E, Aaen G, Belman A, Benson L, Candee M, Chitnis T, Gorman M, Goyal M, Greenberg B, Harris Y, Hart J, Kahn I, Krupp L, Lotze T, Mar S, Moodley M, Ness J, Nourbakhsh B, Rensel M, Rodriguez M, Rose J, Rubin J, Schreiner T, Tillema JM, Waldman A, Weinstock-Guttman B, Casper TC, Waltz M, Graves JS; Network of Pediatric Multiple Sclerosis Centers..Early infectious exposures are not associated with increased risk of pediatric-onset multiple sclerosis. Mult Scler Relat Disord. 2018;22:103-107. doi:10.1016/j.msard.2018.03.015 (05/2018) (link)
  • Azary S, Schreiner T, Graves J, Waldman A, Belman A, Guttman BW, Aaen G, Tillema JM, Mar S, Hart J, Ness J, Harris Y, Krupp L, Gorman M, Benson L, Rodriguez M, Chitnis T, Rose J, Barcellos LF, Lotze T, Carmichael SL, Roalstad S, Casper CT, Waubant E. Contribution of dietary intake to relapse rate in early paediatric multiple sclerosis. J Neurol Neurosurg Psychiatry. 2018;89(1):28-33. doi:10.1136/jnnp-2017-315936 (01/2018) (link)
  • Lavery AM, Waldman AT, Charles Casper T, Roalstad S, Candee M, Rose J, Belman A, Weinstock-Guttman B, Aaen G, Tillema JM, Rodriguez M, Ness J, Harris Y, Graves J, Krupp L, Benson L, Gorman M, Moodley M, Rensel M, Goyal M, Mar S, Chitnis T, Schreiner T, Lotze T, Greenberg B, Kahn I, Rubin J, Waubant E; U.S. Network of Pediatric MS Centers. Examining the contributions of environmental quality to pediatric multiple sclerosis. Mult Scler Relat Disord. 2017;18:164-169. doi:10.1016/j.msard.2017.09.004 (11/2017) (link)
  • Pakpoor J, Seminatore B, Graves JS, Schreiner T, Waldman AT, Lotze TE, Belman A, Greenberg BM, Weinstock-Guttman B, Aaen G, Tillema JM, McDonald JC, Hart J, Ness JM, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Chitnis T, Mar S, Kahn I, Rose J, Carmichael SL, Roalstad S, Waltz M, Casper TC, Waubant E; US Network of Pediatric Multiple Sclerosis Centers. Dietary factors and pediatric multiple sclerosis: A case control study. Mult Scler. 2017 Jun 1 [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/28608728 (06/2017) (link)
  • Gianfrancesco MA, Stridh P, Rhead B, Shao X, Xu E, Graves JS, Chitnis T, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Mar S, Kahn I, Rose J, Roalstad S, Casper TC, Shen L, Quach H, Quach D, Hillert J, Bäärnhielm M, Hedstrom A, Olsson T, Kockum I, Alfredsson L, Metayer C, Schaefer C, Barcellos LF, Waubant E; Network of Pediatric Multiple Sclerosis Centers. Evidence for a causal relationship between low vitamin D, high BMI, and pediatric-onset MS. Neurology. 2017 Apr 25;88(17):1623-1629. https://www.ncbi.nlm.nih.gov/pubmed/28356466 (04/2017) (link)
  • Bourne T, Waltz M, Casper TC, Kavak K, Aaen G, Belman A, Benson L, Candee M, Chitnis T, Graves J, Greenberg B, Gorman M, Harris Y, Krupp L, Lotze T, Mar S, Ness J, Olsen C, Roalstad S, Rodriguez M, Rose J, Rubin J, Schreiner T, Tillema JM, Kahn I, Waldman A, Barcellos L, Waubant E, Weinstock-Guttman B; US Network of Pediatric MS Centers. Evaluating the associaton of allergies with multiple sclerosis susceptibility risk and disease activity in a pediatric population. J Neurol Sci. 2017 Apr 15;375:371-375. https://www.ncbi.nlm.nih.gov/pubmed/28320170 (04/2017)
  • Chitnis T, Graves J, Weinstock-Guttman B, Belman A, Olsen C, Misra M, Aaen G, Benson L, Candee M, Gorman M, Greenberg B, Krupp L, Lotze T, Mar S, Ness J, Rose J, Rubin J, Schreiner T, Tillema J, Waldman A, Rodriguez M, Casper C, Waubant E; U.S. Network of Pediatric MS Centers. Distinct effects of obesity and puberty on risk and age at onset of pediatric MS. Ann Clin Transl Neurol. 2016 Nov 4;3(12):897-907. https://www.ncbi.nlm.nih.gov/pubmed/28097202 (12/2016) (link)
  • Belman AL, Krupp LB, Olsen CS, Rose JW, Aaen G, Benson L, Chitnis T, Gorman M, Graves J, Harris Y, Lotze T, Ness J, Rodriguez M, Tillema JM, Waubant E, Weinstock-Guttman B, Casper TC; US Network of Pediatric MS Centers. Characteristics of Childrena and Adolecents with Multiple Sclerosis. Pediatrics. 2016 Jul;138(1) https://www.ncbi.nlm.nih.gov/pubmed/27358474 (07/2016) (link)
  • McDonald J, Graves J, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Lulu S, Ness J, Harris Y, Rubin J, Candee M, Krupp LB, Gorman M, Benson L, Rodriguez M, Chitnis T, Mar S, Barcellos LF, Laraia B, Rose J, Roalstad S, Simmons T, Casper TC, Waubant E. A case-control study of dietary salt intake in pediatric-onset multiple sclerosis. Mult Scler Relat Disord. 2016 Mar;6:87-92 https://www.ncbi.nlm.nih.gov/pubmed/27063630 (03/2016) (link)
  • Chitnis T, Ness J, Krupp L, Waubant E, Hunt T, Olsen CS, Rodriguez M, Lotze T, Gorman M, Benson L, Belman A, Weinstock-Guttman B, Aaen G, Graves J, Patterson M, Rose JW, Casper TC, Clinical features of neuromyelitis optica in children: US Network of Pediatric MS Centers report. Neurology. 2016 Jan 19; 86(3): 245-52 https://www.ncbi.nlm.nih.gov/pubmed/26683648 (01/2016) (link)
  • Casper TC, Rose JW, Roalstad S, Waubant E, Aaen G, Belman A, Chitnis T, Gorman M, Krupp L, Lotze TE, Ness J, Patterson M, Rodriguez M, Weinstock-Guttman B, Browning B, Graves J, Tillema JM, Benson L, Harris Y; US Network of Pediatric Multiple Sclerosis Centers. The US Network of Pediatric Multiple Sclerosis Centers: Development, Progress, and Next Steps. J Child Neurol. 2015 Sep;30(10):1381-7. https://www.ncbi.nlm.nih.gov/pubmed/25270659 (09/2015) (link)
  • Graves J, Grandhe S, Weinfurtner K, Krupp L, Belman A, Chitnis T, Ness J, Weinstock-Guttman B, Gorman M, Patterson M, Rodriguez M, Lotze T, Aaen G, Mowry EM, Rose JW, Simmons T, Casper TC, James J, Waubant E; US Network of Pediatric Multiple Sclerosis Centers. Protective environmental factors for neuromyelitis optica.  Neurology. 2014 Nov 18;83(21):1923-9.  https://www.ncbi.nlm.nih.gov/pubmed/25339213 (11/2014) (link)
  • Colbert CA, Holshouser BA, Aaen GS, Sheridan C, Oyoyo U, Kido D, Ashwal S. Value of cerebral microhemorrhages detected with susceptibility-weighted MR Imaging for precition of long-term outcome in children with nonaccidental trauma. Radiology. 2010 Sep;256(3):898-905. https://www.ncbi.nlm.nih.gov/pubmed/20720073 (09/2010) (link)
  • Ho A, Michelson D, Aaen G, Ashwal S. Cerebral folate deficiency presenting as adolescent catatonic schizophrenia. J Child Neurol. 2010 Jul;25(7):898-900. https://www.ncbi.nlm.nih.gov/pubmed/20445197 (07/2010) (link)
  • Aaen GS, Holshouser BA, Sheridan C, Colbert C, McKenney M, Kido D, Ashwal S. Magnetic resonance spectroscopy predicts outcomes for children with nonaccidental trauma. Pediatrics. 2010 Feb;125(2):295-303. https://www.ncbi.nlm.nih.gov/pubmed/20123781 (02/2010) (link)

Abstract

  • Aaen G S, Waltz M, Casper T, Ness J, Gorman M, . . . U S Network Paediat Multiple. (2015). Acquisition of early developmental milestones and need for special education services in paediatric-onset multiple sclerosis. Multiple Sclerosis Journal, 21, 83-84. (09/2015)
  • Aaen G, Michelson D, De La Pena W, Przekop A, Roddy S, Shu S, & Ashwal S. (2012). Anti-NMDA Receptor Encephalitis in Children Is Associated with Variable Outcome. Neurology, 78, . (04/2012)
  • Holshouser B, Aaen G, Colbert C, Sheridan C, Oyoyo U, Kido D, & Ashwal S. (2009). LACTATE AND DECREASED NAA PREDICT LONG TERM OUTCOME BETTER THAN PRESENCE OF MICROHEMORRHAGES SEEN WITH SUSCEPTIBILITY WEIGHTED IMAGING (SWI) AFTER NONACCIDENTAL TRAUMA (NAT). Journal of Neurotrauma, 26(8), A15-A15. (08/2009)