Research Projects & Grants

For Profit Organization

  • The Ex-vivo Removal of Soluble PD-LI, Total Extracellular Vesicles (EVs), and EVs Positive for PD-LI by the Aethlon Hemopurifier from Discarded Plasma in Patients Undergoing Total Plasma Exchange (TPE), Role: PI, Aethlon Medical, Inc., (11/2023) Status: Approved
  • A Phase 2, Randomized, Double-blind, Placebo-controlled, Dose-finding Study to Evaluate the Efficacy and Safety of ALXN2050 in Adult Participants with Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN), Role: Investigator, Alexion Pharmaceuticals, (08/2023 - 08/2024) Status: Approved
  • A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy and Safety of Sibeprenlimab Administered Subcutaneously in Subjects with Immunoglobulin A Nephropathy, Role: Investigator, Otsuka Pharmaceuticals, (08/2023 - 08/2024) Status: Approved
  • A phase 3 prospective, randomized, multi-center, open-label, controlled trial to assess the efficacy and safety of cellular immunotherapy with MDR-101 for induction of immune tolerance in recipients of HLA-matched, living donor kidney transplants, Role: Investigator, Medeor Therapeutics, Inc., (05/2023 - 05/2024) Status: Approved
  • Treatment of drug-resistant adult and pediatric primary focal segmental glomerulosclerosis using the Liposorber LA-15 System, Role: Investigator, Kaneka Medical America LLC, (05/2023 - 05/2024) Status: Approved
  • A 24 month, multicenter,randomized, open-label safety and efficacy study of concentration-controlled everolimus with reduced calcineurin inhibitor vs mycophenolate with standard calcineurin inhibitor in denovo renal transplant- advancing renal transplant efficacy and safety outcomes with an eveRolimus- based regimen (TRANSFORM, Jan 2015), Role: Investigator, Novartis Pharmaceuticals Corporation, (02/2018 - 02/2019) Status: Completed
  • Evaluating the use of polymyxin B hemoperfusion in a randomized controlled trial of adults treated for endotoxemia and septic shock (EUPHRATES), Role: Investigator, Spectral Diagnostics Inc., (07/2014 - 07/2015) Status: Completed

Internal

  • Evaluation of PKD diagnosis impact on the patients' quality of life, Role: Investigator, LLU Dept. of Medicine, (11/2023) Status: Approved
  • HRQOL in Patients with Lupus Nephritis and IgA Nephropathy, Role: Investigator, LLU Dept. of Medicine, (12/2023) Status: Approved
  • Distress Tolerance in Lupus Nephritis; Exploring the Impact of Acceptance on Disease Severity, Role: Investigator, LLU Dept. of Medicine, (09/2023) Status: Approved
  • Cardiovascular risk management in lupus nephritis and IgA nephropathy patients, Role: Investigator, LLU Dept. of Medicine, (03/2023) Status: Approved
  • Toe-brachial and ankle-brachial index and angiographically determined lower extremity arterial disease in patients with end-stage kidney disease on dialysis therapy and the respective association with subsequent amputation, Role: Investigator, LLU Dept. of Medicine, (07/2022) Status: Approved
  • Extracorporeal Photopheresis in heart transplant rejection at LLUMC, Role: PI, LLU Dept. of Medicine, (06/2021) Status: Approved
  • Role of lithium in depression and suicidal ideation in end stage renal disease patients, Role: Investigator, LLU Dept. of Pharmacy Practice, (07/2021) Status: Approved
  • A multi-site glomerular diseases registry, Role: Investigator, LLU Dept. of Medicine, (03/2021) Status: Approved
  • Assessment of kidney disease in COVID-19 patients during hospitalization and post recovery, Role: Investigator, LLU Dept. of Medicine, (02/2021) Status: Approved
  • Blood sampling for patients of interest for COVID-19, Role: PI, LLU Dept. of Anesthesiology, (02/2021) Status: Approved
  • Demystifying allergic reactions of Angiotensin Converting Enzyme inhibitors (ACEi) in patients receiving apheresis, Role: PI, LLU Dept. of Medicine, (02/2019) Status: Approved
  • Septic Shock and Early Goal Directed Therapy in Patients with End Stage Renal Disease, Role: PI, LLU Dept. of Medicine, (12/2015) Status: Completed
  • Role of lithium in depression and suicidal ideation in end stage renal disease patients, Role: Other Significant Contributor, LLU - GRASP, (01/2021 - 12/2024) Status: Awarded