Publications

Scholarly Journals--Accepted

  • Phase 3 Study of the Efficacy, Pharmacokinetics, Immunogenicity and Safety of von Willebrand Factor/Factor VIII Concentrate in Patients with Severe von Willebrand Disease under 6 Years of Age.  International Society of Hemostasis & Thrombosis , RPTH journal June 2023 (07/2023)
  • Jain A; Reactivation of factor 8 inhibitor on emicizumab prophylaxis in a previously tolerized patient; HTRS 2023 Scientific Symposium Orlando 3/2023; Research and Practice in Thrombosis and Hemostasis 3/2023 in press. (03/2023)

Abstract

  • Gray, Austin L. MD*; Liu, Yan MD, PhD*; Wappler-Guzzetta, Edina A. MD, PhD*; Cherukuri, Durga PhD*; Wang, Jun MD*; Jain, Akshat MD†. Case Report of a Myeloid Neoplasm with Pathogenic Germline Variant in DDX41 and Constitutional inv (7) (q11.2q22) Along with JAK2 Pathogenic Variant in a 9-Year-Old Patient Who Presented With Features of Essential Thrombocythemia. Journal of Pediatric Hematology/Oncology ():10.1097/MPH. 02681, May 22, 2023. | DOI: 10.1097/MPH. 02681 (06/2023)
  • JAMA oncology   Martin SD, Davis ES, Dai C, Jain A (POCC COVID consortium) et al. Clinical Features and Risk Factors Associated with Multisystem Inflammatory Syndrome in Children with Cancer and COVID-19. JAMA Oncol. Published online May 11, 2023. doi:10.1001 Martin SD, Davis ES, Dai C, Jain A (POCC COVID consortium) et al. Clinical Features and Risk Factors Associated with Multisystem Inflammatory Syndrome in Children with Cancer and COVID-19. JAMA Oncol. Published online May 11, 2023. doi:10.1001/JAMA oncology.2023.0525 (05/2023)
  • Patrick Zacharais, Latika Puri, Akshat Jain; Hematological Alterations in Patients of Multisystem Inflammatory Syndrome in Children (MIS-C) a Risk Prediction Analysis Based on a Single Center Experience. American Academy of Pediatrics NCE 2022, 10/22. (10/2022)
  • Patient Reported Outcomes to Assess Quality of Hemophilia Care in North India - Results of a Global Partnership Global Hematology & Oncology  Blood (2016) 128 (22): 3587. (12/2016) (link)
  • Non-Myeloablative Conditioning Targeting Host Immunosuppression Is Successful in Matched Sibling Donor Stem Cell Transplantation for Hemoglobinopathies in Children Blood (2014) 124 (21): 3873. (08/2014) (link)

Scholarly Journals--Published

  • Jain Akshat, Patel A, Winters T; A Rare Report of the Coexistence of Sickle Cell Disease, Neurofibromatosis Type 1, and Intracranial Hypertension in a Pediatric Patient; Journal of Pediatric Hematology/Oncology   Patel, Amie DO*; Winter, Timothy DO†; Jain, Akshat MD*,‡. A Rare Report of the Coexistence of Sickle Cell Disease, Neurofibromatosis Type 1, and Intracranial Hypertension in a Pediatric Patient. Journal of Pediatric Hematology/Oncology 45(3):p 155-158, April 2023. | DOI: 10.1097/MPH.0000000000002647 (04/2023)
  • SARS-CoV-2 in Childhood Cancer in 2020: A Disease of Disparities. Journal of Clinical Oncology Johnston EE, Martinez I, Davis ES, Caudill C, Richman J, Brackett J, Dickens DS, Kahn A, Schwalm C, Sharma A, Patel PA, Bhatia S, Levine JM, Wolfson JA; POCC Consortium( Jain Akshat etal.).  (12/2021) (link)
  • Sickle Cell Disease with Dermatomyositis-a Rare and Complex Comorbidity https://ashpublications.org/blood/article/138/Supplement%201/4174/477662 (11/2021) (link)
  • Impact of COVID 19 Pandemic on Health Care Utilization for Patients with Sickle Cell Disease-a Specialty Treatment Center Experience Starting in March 2020, the coronavirus 19 disease (COVID-19) pandemic affected the United States (US) health care system. Many individuals were afraid to seek medical care due to fear of obtaining COVID-19; therefore, there was a high frequency of adults forgoing medical care. Chronic conditions including diabetes, COPD, mental health, and HTN outcomes worsened due to decrease in routine care during the pandemic. Sickle cell disease (SCD) is a chronic blood disorder that causes numerous complications including but not limited to vaso-occlusive crisis, strokes, and chronic kidney disease. Individuals who have routine follow up with a hematologist have been shown to have decreased hospitalizations, ER visits, length of stay, and opiate usage. (11/2021) (link)
  • Jain A., Establishing Cost effective strategies for predicting outcomes of Pediatric leukemia’s. Jain A., Establishing Cost effective strategies for predicting outcomes of Pediatric leukemia’s.; Journal of Pediatric Hematology Oncology; JPHO-20-209, Invited Editorial. (05/2020) (link)
  • Challenges in Management of Severe Hemophilia with Acute Hematologic Malignancies (10/2019)
  • Editorial : Oxidant Health in Sickle Cell Disease The understanding of the role that hypoxic injury , endothelial dysfunction , cellular activation play in the evolution of a sickle cell disease will start with validating a scientific instrument to measure such markers in the human body accurately. Editorial discusses the current knowledge of the issue in literature and the proposed interventions to ameliorate it as a potential etiology for Sickle Cell Disease Crisis .  (09/2018) (link)

Book Review - Scholarly Journals--Published

  • Foreward to the Book : The Many Faces and Lives of Sickle Cell - A Global Collaboration Hardcover . ISBN-10 ‏ : ‎ 0645413429 ISBN-13 ‏ : ‎ 978-0645413427 (06/2022)

Books and Chapters

  • Textbook: Thalassemia Updates and Novel Developments ISBN: 978-1-83969-158-4, Print ISBN: 978-1-83969-157-7, eBook (PDF) ISBN: 978-1-83969-159-1, 2020 (10/2021)
  • Thrombocytopenia of Childhood; Monograph on Platelet disorders Authors Akshat Jain, James Bussel     Book : Textbook of the Indian College of Physicians(ICP) /Association of Physicians of India ( API ) (07/2015) (link)

Non-Scholarly Journals

  • Childhood Covid-19 illness – Early detection is the key. This pandemic has confined people everywhere to the indoors to control keep the virus from spreading. Older adults have been the most commonly affected age group by the virus, but more recently a strange presentation of Covid-19 has been seen in children. New York City reported 15 similar cases between April 16 and May 4 for the first time in the United States. The state health officials were investigating 102 cases as of May 12. Multiple reports Thereafter, other US states and other countries reported similar symptoms and presentations in children who also were testing positive for Covid. It mirrors the presentation of a dramatic disease of children, called Kawasaki Disease, wherein the body goes into an overdrive leading to over-activation of inflammation. This new disease has been called  Multisystem inflammatory syndrome in children (MIS-C) and the CDC recently issued guidance to diagnose children with MIS-C if they have, Age <21 years with fever, laboratory evidence of inflammation and evidence of clinically severe illness requiring hospitalization with multisystem (>2) organ involvement (cardiac, renal, respiratory, hematologic, gastrointestinal, dermatologic or neurological); and No alternative plausible diagnoses; and Positive for current or recent SARS-CoV-2 infection by reverse-transcriptase polymerase chain reaction, serology or antigen test; or COVID-19 exposure within the four weeks prior to the onset of symptoms.   Simply put, if a child develops high grade fever (100.4 degree F or higher), fever, a rash, swollen hands and feet, red eyes, swollen lymph nodes and red, swollen or cracked lips, mouth, throat and tongue etc., immediate help with the pediatrician / family doctor should be sought to identify the case and early treatment leads to full recovery in children in most cases. Delay can lead to life-threatening cardiac complications. Treatment with medications called as Immunoglobulins and supportive care in a hospital setting is needed. (05/2020) (link)

Scholarly Journals--Submitted

  • Inflammatory “Endotheliopathy’ with COVID 19 infections in children, unanswered questions for management post recovery. THE LANCET -Jain A., Soneji M.; Inflammatory “Endotheliopathy’ with COVID 19 infections in children, unanswered questions for management post recovery. Lancet May 2020 :THELANCET-D-20-11039 (05/2020) (link)

Online Publications

  • Global Hematology - A Levelled Playing field  Speical Feature for American Society of Pediatric Hematology Oncology , invited Editorial : A review of Care Delivery and Challenges that face the world and patients with Hemoglobinopathies , Anemia , bleeding disoreders amongst other lifelong chronic disesaes that are a major cost for health delivery globally .  Exchange of information to initiate capacity building, care coordination, and jointresearch has the potential to ameliorate the challenge of access to specializedcare globally. It is most fitting to the field of benign hematology especially giventhe disparity in patient to practitioner ratio in resource limited settings. The wideavailability of mobile devices and internet access even in the remotest areas ofthe world provides a unique opportunity to coordinate care and provideemergency access to patients globally. (06/2018)