Publications

Abstract

  • Hughes L, Hasaniya N, Bailey L and Kearns-Jonker M. Prostaglandin E2 Induces YAP1 and Agrin via EP4 in Islet-1+ Stem Cells that Improve Cardiac Repair in a Sheep Model of Myocardial Infarction.  Accepted for oral presentation at the upcoming IPITA-International Xenotransplant Association- Cell Transplant and Regenerative Medicine Society meeting October 2023. (10/2023)
  • Vega R, Hughes L, Hasaniya N, Bailey LL and Kearns-Jonker M. Periostin Is Induced During Cell-Based Repair in the Sheep Mondel of Myocardial Infarction, American Heart Association BCVS meeting, July 2023 (07/2023)

Scholarly Journals--Published

  • Knox C, Garcia K, Tran J, Wilson S, Blood A, Kearns--Jonker M, Martens T. A Biomimetic Approach Utilizing Pulsatile Perfusion Generates Contractile Vascular Grafts. Tissue Eng Part A. 2023 29(13-14):358-371. doi: 10.1089/ten.TEA.2022.0206. Epub 2023 May 23.PMID: 37071180 (05/2023)
  • Ceja L, Escopete S, Hughes L, Lopez LV, Camberos V, Vallejos P, Wall N and Kearns-Jonker M. Neonatal Cardiovascular Progenitor Cell-Derived Extracellular Vesicles Activate YAP1 In Adult Cardiac Progenitor Cells.  Int J.Mol.Sci. 2023 Apr 30;24(9):8088. doi: 10.3390/ijms24098088.PMID: 37175796 (04/2023)
  • Veliz A, Mamoun L, Hughes L, Vega R, Holmes B, Monteon A, Bray J, Pecaut MJ and Kearns-Jonker M. Transcriptomic Effects on the Mouse Heart Following 30 Days on the International Space Station.  Biomolecules 2023  Feb 15;13(2):371. doi: 10.3390/biom13020371 (02/2023)
  • Monteon A, Hughes L, Camberos V, Kearns-Jonker M. Identification of SALL4 Expressing Islet-1+ Cardiovascular Progenitor Cell Clones. International Journal of Molecular Sciences 2023; Jan 16;24(2):1780. doi: 10.3390/ijms24021780.PMID: 36675298. (01/2023)
  • Lopez L, Camberos V, Bailey LL, Hasaniya N, Hughes L, Knox C, and Kearns-Jonker M.  MicroRNA Expression in the Infarcted Heart Following Neonatal Cardiovascular Progenitor Cell Transplantation in a Sheep Model of Stem Cell-Based Repair Cell Transplantation 2022 Jan-Dec;31:9636897221136787. doi: 10.1177/09636897221136787. PMID: 36564913. (10/2022)
  •   1.       Sharma A, Clemens RA, Garcia O, Taylor DL, Wagner NL, Shepard KA, Gupta A, Malany S, Grodzinsky AJ, Kearns-Jonker M, Mair DB, Kim DH, Roberts MS, Loring JF, Hu J, Warren LE, Eenmaa S, Bozada J, Paljug E, Roth M, Taylor DP, Rodrigue G, Cantini P, Smith AW, Giulianotti MA, Wagner WR. Biomanufacturing in low Earth orbit for regenerative medicine. Stem Cell Reports. 2021 Dec 16:S2213-6711(21)00598-1. doi: 10.1016/j.stemcr.2021.12.001. Epub ahead of print. PMID: 34971562. (12/2021)
  • Knox C, Camberos V, Ceja L, Monteon A, Hughes L, Longo L and Kearns-Jonker M. Long-Term Hypoxia Maintains a State of Dedifferentiation and Enhanced Stemness in Fetal Cardiac Progenitor Cells Int J Mol Sci. 2021 Aug 29;22(17):9382. doi: 10.3390/ijms22179382. PMID: 34502291 (08/2021)
  • Camberos V, Baio J, Mandujano A, Martinez AF, Bailey L, Hasaniya N, Kearns-Jonker M. The Impact of Spaceflight and Microgravity on the Human Islet-1+ Cardiovascular Progenitor Cell Transcriptome  Int. J. Mol. Sci. 2021, 22, 3577. https://doi.org/10.3390/ijms22073577 (03/2021)
  • Camberos V, Baio J, Bailey L, Hasaniya N, Lopez LV, Kearns-Jonker M  Effects of spaceflight and simulated microgravity on YAP1 expression in cardiovascular progenitors: Implications for cell-based repair Int J Mol Sci. 2019 Jun 4;20(11). pii: E2742. doi: 10.3390/ijms20112742.PMID:31167392 (06/2019)
  • Baio J, Martinez AF, Silva I, Hoehn CV, Countryman S, Bailey L, Hasaniya N, Pecaut M, Kearns-Jonker M. Cardiovascular progenitor cells cultured aboard the International Space Station exhibit altered developmental and functional properties    NPJ Microgravity  2018 Jul 26;4:13 doi: 10.1038/s41526-018-0048-x. eCollection 2018 PMID: 30062101 (07/2018)
  • Hernandez I, Baio J, Tsay E, Martinez A, Fuentes T, Bailey L, Hasaniya N, and Kearns-Jonker M. Short-term hypoxia improves early cardiac progenitor cell function in vitro.  American Journal of Stem Cells Feb 1;7(1):1-17. eCollection 2018.PMID:29531855 (02/2018)
  • Baio J, Martinez AF, Bailey LL, Hasaniya N, Pecaut M, Kearns-Jonker MSpaceflight Activates Protein Kinase C Alpha Signaling and Modifies the Developmental Stage of Human Neonatal Cardiovascular Progenitor Cells. Stem Cells Dev. 2018 Jan 10. Jun 15;27(12):805-818. doi: 10.1089/scd.2017.0263. Epub 2018 Feb 12.PMID:29320953   (01/2018)
  • Baio J, Walden R,  Lee C, Hasaniya N, Bailey LB, and Kearns-Jonker M.  A polysaccharide polymer scaffold facilitates cardiac stem cell proliferation and lineage commitment. Transplantation Direct 2017Apr 13;3(5):e153. doi: 10.1097/TXD.0000000000000667. eCollection 2017 May. PMID: 28573188: PMC5441984 (03/2017)
  • Stewart JM, Tarantal AF, Hawthorne WJ, Salvaris EJ, O'Connell PJ, Nottle MB, d'Apice AJ, Cowan PJ, Kearns-Jonker M. Clonidine inhibits anti-non-Gal IgM xenoantibody elicited in multiple pig-to-primate models. Xenotransplantation. 2015 Nov-Dec;22(6):413-26. PubMed PMID: 26490547; PubMed Central PMCID: PMC4902317. (11/2015)
  • Fuentes TI, Appleby NA, Raya M, Bailey LB, Hasaniya L, Kearns-Jonker M. Microgravity exerts an age-dependent effect on the differentiation of cardiovascular progenitors isolated from the human heart. PLOS One Jul 10;10(7):e0132378. 2015. (07/2015)
  • JM Stewart, AF Tarantal, WJ Hawthorne, EJ Salvaris, PJ O’Connell, MB Nottle, AJF d’Apice, PJ Cowan and M Kearns-Jonker.  “Rhesus monkeys and baboons develop FVIII inhibitors in response to GTKO endothelial cells and porcine islets” Xenotransplantation, 2014 May 8. doi: 10.1111/xen.12100. [Epub ahead of print]PMID:24806998 (05/2014)
  • Chen Y, Stewart J, Gunthart M, Salvaris EJ, Hawthorne WJ, O’Connell PJ, Nottle MB, d’Apice AJF, Cowan PJ, and Kearns-Jonker M. Xenoantibody Response to Porcine Islet Cell Transplantation to Baboons using GalTKO, CD 55, CD59, and Fucosyl-Transferase Multiple Transgenic Donors, Xenotransplantation, May;21(3):244-53. 2014 PMID: 24625827   Xenotransplantation 2014 May;21(3):244-53. doi: 10.1111/xen.12091. Epub 2014 Mar 20. PMID:24645827 (05/2014)
  • Stewart JM, Chen Y, Fuentes TI, Appleby N, Tarantal AF, Salvaris E, Cowan P, d’Apice A, and  Kearns-Jonker M. “Anti-nonGal specific combination treatment with an anti-idiotypic Ab and an inhibitory small molecule mitigates the xenoantibody response”,  Xenotransplantation,  May ; 21(3) 254-66, 2014. PMID: 24635144 (05/2014)
  • Su RJ, Baylink DJ, Neises A, Meng X, Kiroyan JB, Payne KJ, Duan Y, Tschudy-Seney B, Appleby N, Kearns-Jonker M, Gridley DS, Wang J, William Lau KH, Zhang XB. Efficient Generation of Integration-Free iPS Cells from Human Adult Peripheral Blood Using BCL-XL Together With Yamanaka Factors Plos One, May 21;8(5):e64496, 2013 PMID: 23704989 (05/2013)
  • Fuentes T, Appleby N, Tsay E, Bailey L, Hasaniya N, and Kearns-Jonker M. Human Neonatal Cardiovascular Progenitors: Unlocking the Secret to Regenerative Ability (05/2013)
  • Fuentes T.I. and Kearns-Jonker M.  Endogenous cardiac stem cells for the treatment of heart failure. Stem Cells and Cloning: Adv and Apps, 2013:6,1 – 12     (03/2013)
  • Hou X, Appleby N, Fuentes T, Longo LD, Bailey LL, Hasaniya N and Kearns-Jonker M. Isolation, characterization and spatial distribution of cardiac progenitor cells in the sheep heart.  J of Clinical and Experimental Cardiology   2012, 3:6. (10/2012)
  • Evans, JM, Navarro S, Doki T, Stewart JM, Mitsuhashi N, and Kearns-Jonker M.  Gene transfer of hemeoxygenase 1 using adeno-associated virus serotype 6 vector prolongs cardiac allograft survival.J Transplantation; 2012, Article ID 740653 (05/2012)
  • Kearns-Jonker M , Dai W, Gunthart M, Fuentes T, Yeh Hsiao-Yun, Gerczuk P, Pera M, Mummery C, and Kloner RA. Genetically Engineered Mesenchymal Stem Cells Influence Gene Expression in Donor Cardiomyocytes and the Recipient Heart J Stem Cell Res and Therapy, 2012,  S1-S8 (01/2012)
  • Kearns-Jonker M, Dai W and Kloner RA. Stem Cells for the Treatment of Heart Failure. Current Opinion in Molecular Therapeutics 12 (4): 432-441, 2010. (07/2010 - 12/2010)

Online Publications

  • Giulianotti MA, Sharma A, Clemens RA, Garcia O, Taylor DL,Wagner NA, Shepard KA, Gupta A, Malany S, Grodzinsky A, Kearns-Jonker M, Mair DB, Kim DH,  Roberts M, Loring J,Hu J, Warren L, Eenmaa S, Bozada J, Paljug E, Roth M, Taylor DP, Rodrigue G,  Cantini P, Smith AW, Wagner W.  Opportunities for Biomanufacturing in Low Earth Orbit: Current Status and Future Directions. Preprints (www.preprints.org) posted August 2, 2021Fdoi:10.20944/preprints202108.0044.v1 (08/2021)