Publications

Scholarly Journals--Published

  • dela Peña IC, Figueroa JD, Shi WX (2022). Hypothesis: Amelioration of obesity-induced cognitive dysfunction via a lorcaserin-betahistine combination treatment. Pharmacology Research and Perspectives. 10(3):e00947. doi: 10.1002/prp2.947. (05/2022) (link)
  • Vega-Torress JD. Ontiveros-Angel P, Terrones E, Stuffle EC, Solak S, Tyner E, Oropeza M, de la Peña IC, Obenaus A, Ford BD, Figueroa JD. (2022). Short-term exposure to an obesogenic diet during adolescence elicits anxiety-related behavior and neuroinflammation: modulatory effects of exogenous neuregulin-1. Translational Psychiatry, 12:83 (02/2022) (link)
  • de la Peña I, Koch J (2021). Teaching Intellectual Humility is Essential in Preparing Collaborative Future Pharmacists. American Journal of Pharmaceutical Education. 8444; DOI: https://doi.org/10.5688/ajpe8444 (01/2021)
  • dela Peña I, Pan MC, Thai CG, Alisso T (2020). Attention-Deficit/Hyperactivity Disorder Predominantly Inattentive Subtype/Presentation: Research Progress and Translational Studies. Brain Sciences. 10(5), 292. (08/2020)
  • dela Peña I, Knecht K, Gavaza P (2020). Impact and Pharmacy Students’ Perception of An Elective Course on Evidence-based Learning Strategies. American Journal of Pharmaceutical Education. DOI: https://doi.org/10.5688/ajpe8232. (08/2020)
  • dela Peña I, Shen G, Shi WX (2020). Droxidopa alters dopamine neuron and prefrontal cortex activity and improves attention-deficit/hyperactivity disorder-like behaviors in rats. European Journal of Pharmacology. 892:173826. (08/2020)
  • Tyner E, Oropeza M, Figueroa J, dela Peña, IC. (2019). Childhood Hypertension and Effects on Cognitive Functions: Mechanisms and Future Perspectives. CNS Neurol Disord Drug Targets. 2019;18(9):677-686 (08/2019)
  • Kim Y, Jeon S, Jeong HJ, Lee SM, dela Pena I et al (2019). Restoration of Cdk5, TrkB and SNARE proteins after chronic MPH treatment in Spontaneous Hypertensive Rats, a model for Attention-deficit Hyperactivity Disorder. Psychiatry Investigation. 2019 Jul; 16(7): 558–564. (07/2019)
  • Knecht T, Borlongan CV, dela Pena I* (2018). Combination therapy for ischemic stroke: Novel approaches to lengthen therapeutic window of tissue plasminogen activator. Brain Circulation. (4): 99-108. (08/2018)
  • dela Pena, I*, Shen GS, Shi WX (2018). Methylphenidate significantly alters the functional coupling between the prefrontal cortex and dopamine neurons in the ventral tegmental area. Neuropharmacology. 131:431-439.     (08/2018)
  • dela Pena I*, Yang S, Shen G, Fang Liang H, Solak S, Borlongan CV (2018). Extension of Tissue Plasminogen Activator Treatment Window by Granulocyte-Colony Stimulating Factor in a Thromboembolic Rat Model of Stroke. Int J Mol Sci. 31:19(6) (08/2018)
  • dela Pena IJI, Botanas CJ, dela Peña JB, Custodio RJ, dela Peña I, et al (2018). The Atxn7-overexpressing mice showed hyperactivity and impulsivity which were ameliorated by atomoxetine treatment: a possible animal model of the hyperactive-impulsive phenotype of ADHD. Prog Neuropsychopharmacol Biol Pscyhiatry. 88:311-319.   (08/2018)
  • dela Peña I*, Borlongan C, Shen G, Davis W (2017). Strategies to Extend Thrombolytic Time Window for Ischemic Stroke Treatment: An Unmet Clinical Need. J Stroke. 19(1):50-60. (08/2017)
  • dela Peña I*, dela Peña IJI, de la Peña JB, Kim HJ, Shin CY, Han DH, Kim BN, Ryu JH, Cheong JH (2017). Methylphenidate and atomoxetine-responsive prefrontal cortical genetic overlaps in “impulsive” SHR/NCrl and Wistar rats. Behav Genet. 47(5): 564-580. (08/2017)
  • dela Peña IJI, dela Peña I, de la Peña JB, Kim HJ, Sohn A, Shin CY, Han DH, Kim BN, Ryu JH, Cheong JH (2017). Transcriptional profiling of SHR/NCrl prefrontal cortex reveals hyperactivity-associated genes responsive to amphetamine challenge. Genes Brain Behav. 16(7): 664-674.   (08/2017)
  • Liska M, dela Peña, I* (2017). Granulocyte-colony stimulating factor and umbilical cord blood cell transplantation: Synergistic therapies for the treatment of traumatic brain injury. Brain Circulation. 3:143-151. (08/2017)
  • Knecht T, Story J, Liu J, Davis W, Borlongan CV, dela Peña I*. 2017. Adjunctive Therapy Approaches for Ischemic Stroke: Innovations to Expand Time Window of Treatment. Int. J. Mol. Sci. 18(12), 2756.   (08/2017)
  • Tajiri N, dela Peña I, Acosta SA, Kaneko Y, Tamir S, Landesman Y, Carlson R, Shacham S, Borlongan CV. (2016) A Nuclear Attack on Traumatic Brain Injury: Sequestration of Cell Death in the Nucleus. CNS Neurosci Ther. 22(4):306-15. (08/2016)
  • Ahn J, Ahn HS, Cheong JH, dela Peña IC* (2016). Natural Product-Derived Treatments for Attention-Deficit/Hyperactivity Disorder: Safety, Efficacy, and Therapeutic Potential of Combination Therapy. Neural Plast. 2016:1320423 (08/2016)
  •   dela Peña IC*, Shi WX (2016). Chemogenetic approach to model hypofrontality. Med Hypotheses. 93:113-116.   (08/2016)
  • de la Peña JB, Ahsan HM, Tampus R, Botanas CJ, Dela Peña IJ, Kim HJ, Sohn A, dela Peña I, Shin CY, Ryu JH, Cheong JH (2015). Cigarette smoke exposure during adolescence enhances sensitivity to the rewarding effects of nicotine in adulthood, even after a long period of abstinence. Neuropharmacology. 99:9-14. (08/2015)
  • dela Peña IC, Yoo A, Tajiri N, Acosta SA, Ji X, Kaneko Y, Borlongan CV (2015). Granulocyte colony-stimulating factor attenuates delayed tPA-induced hemorrhagic transformation in ischemic stroke rats by enhancing angiogenesis and vasculogenesis. J Cereb Blood Flow Metab. 35(2):338-46. (08/2015)
  • dela Peña IC, Sanberg PR, Acosta SA, Lin SZ, Borlongan CV (2015). G-CSF as an adjunctive therapy with umbilical cord blood cell transplantation for traumatic brain injury. Cell Transplant.  24(3):447-57.   (08/2015)
  • dela Peña IC*, Gevorkiana R, Shi WS (2015). Psychostimulants affect dopamine transmission through both dopamine transporter-dependent and independent mechanisms. Eur J Pharmacol. 764:562-70.   (08/2015)
  • dela Peña IC*, Bang M, Lee J, de la Peña JB, Kim BN, Han DH, Noh M, Shin CY, Cheong JH (2015). Common prefrontal cortical gene expression profiles between adolescent SHR/NCrl and WKY/NCrl rats which showed inattention behavior. Behav Brain Res. 291:268-276.   (08/2015)
  • dela Peña IC, de la Peña JB, Kim BN, Han DH, Noh M, Cheong JH (2015). Gene expression profiling in the striatum of amphetamine-treated spontaneously hypertensive rats which showed amphetamine conditioned place preference and self-administration. Arch Pharm Res. 38(5):865-75.   (08/2015)
  • Lozano D, Gonzales-Portillo GS, Acosta S, de la Pena I, Tajiri N, Kaneko Y, Borlongan CV. (2015). Neuroinflammatory responses to traumatic brain injury: etiology, clinical consequences, and therapeutic opportunities. Neuropsychiatr Dis Treat. 8;11:97-106.   (08/2015)
  • dela Peña IC, Gonzales EL, de la Peña JB, Kim BN, Han DH, Shin CY, Cheong JH (2015). Individual differences in novelty-seeking behavior in spontaneously hypertensive rats: Enhanced sensitivity to the reinforcing effect of methylphenidate in the high novelty-preferring subpopulation. J Neurosci Methods 252:48-54.   (08/2015)
  • Acosta SA, Tajiri N, dela Peña I, Bastawrous M, Sanberg PR, Kaneko Y, Borlongan CV (2015). Alpha-synuclein as a pathological link between chronic traumatic brain injury and Parkinson's disease. J Cell Physiol.230(5):1024-32. (08/2015)
  • dela Peña IC*, Borlongan CV (2015). Translating G-CSF as an Adjunct Therapy to Stem Cell Transplantation for Stroke. Transl Stroke Res. 2015, 6(6): 421-429 (08/2015)
  • Tajiri N, Acosta S, Portillo-Gonzales GS, Aguirre S, Reyes S, dela Peña IC, et al., (2014). Therapeutic outcomes of transplantation of amniotic fluid-derived stem cells in experimental ischemic stroke. Front Cell Neurosci 13;8:227. (08/2014)
  • Pabon M, Tamboli C, Tamboli S, Pabon M, Acosta S, dela Peña IC, Sanberg P, Tajiri N, Kaneko Y, Borlongan C (2014) Estrogen replacement therapy for stroke. Cell Med 6:111-122. (08/2014)
  • Tajiri N, Duncan K, Borlongan MC, Pabon M, Acosta S, dela Peña I, et al. (2014). Adult stem cell transplantation: is gender a factor in stemness? Int J Mol Sci 15(9):15225-15243. (08/2014)
  • dela Peña IC, Sanberg PR, Acosta SA, Tajiri N, Lin SZ, Borlongan CV (2014). Stem cells and G-CSF for treating neuroinflammation in traumatic brain injury: aging as a co-morbidity factor. J. Neurosurg Sci. 58(3): 143-149. (08/2014)
  • dela Peña IC, Sanberg PR, Acosta SA, Lin SZ, Borlongan CV (2014). Umbilical cord blood cell and G-CSF: combination therapy for traumatic brain injury. Regen Med 9(4):409-12.   (08/2014)
  • Tajiri N, Duncan K, Antoine A, Pabon M, Acosta S, dela Peña I, et al. (2014). Stem cell-paved biobridge facilitates neural repair in traumatic brain injury. Front Syst Neurosci 24;8:116.  (08/2014)
  • dela Peña IC, Pabon M, Acosta S, Sanberg P, Tajiri N, Kaneko Y, Borlongan CV (2014). Oligodendrocytes engineered with migratory proteins as effective graft source for cell transplantation in multiple sclerosis. Cell Med 6:123-127.   (08/2014)
  • Lin D, dela Peña IC, Lin L, Zhou SF, Borlongan CV (2014). The neuroprotective role of acupuncture and activation of the BDNF signaling pathway. Int J Mol Sci 15(2): 3234-3252. (08/2014)
  • dela Peña IC, Kim HJ, Sohn AR, Kim BN, Han DH, Ryu JH, Shin CY, Noh MS, Cheong JH (2014). Prefrontal cortical and striatal transcriptional responses to the reinforcing effect of repeated methylphenidate treatment in the spontaneously hypertensive rat, animal model of attention-deficit/hyperactivity disorder (ADHD). Behav Brain Funct 10:17.   (08/2014)
  • dela Peña IC, Sanberg PR, Acosta SA, Tajiri N, Lin SZ, Borlongan CV (2014). Stem cells and G-CSF for treating neuroinflammation in traumatic brain injury: aging as a co-morbidity factor. J Neurosurg Sci 58(3):145-9.   (08/2014)
  • Poulos SG, Richie WD, Bailey RK, Lee A, dela Peña I, Sanberg PR, Borlongan CV (2014). The potential of neural stem cell transplantation for the treatment of fetal alcohol spectrum disorder. Prog Neuropsychopharmacol Biol Psychiatry. 54C:149-156.   (08/2014)
  • Yoon SY, dela Peña IC, Kim SM, Woo TS, Shin CY, Son KH, Park H, Lee YS, Ryu JH, Jin M, Kim KM, Cheong JH (2013). Oroxylin A improves attention deficit hyperactivity disorder-like behaviors in the spontaneously hypertensive rat and inhibits reuptake of dopamine in vitro. Arch Pharmacal Res 36:134-140. (08/2013)
  • dela Peña IC, Cheong JH (2013). Abuse and dependence liability analysis of methylphenidate in the spontaneously hypertensive rat model of attention-deficit/hyperactivity disorder (ADHD): what have we learned?. Arch Pharmacal Res 36(4):400-10.   (08/2013)
  • dela Peña, IC. Yoon S.Y. Kim Y, Park H, Kim KM, Ryu JH, Shin CY, Cheong JH (2013). 5,7- dihydroxy-6-methoxy-4'-phenoxyflavone, a derivative of oroxylin A improves attention-deficit/hyperactivity disorder (ADHD)-like behaviors in spontaneously hypertensive rats. Eur J Pharmacol 715(1-3):337-344. (08/2013)
  • dela Peña JB, dela Peña IJ, Lee HL, dela Peña IC, Shin CY, Sohn AE, Cheong JH (2013). Pre-exposure to ethanol, but not to caffeine and nicotine,induced place preference and self-administration of the NMDA receptor antagonist-benzodiazepine combination, Zoletil. Pharmacol Biochem Behav 110:231-237.   (08/2013)
  • Kim KS, Shim WS, dela Peña IC, Seo EK, Kim WY, Jin HE, Kim DD, Chung SJ, Cheong JH, Shim CK. (2013) Smooth muscle relaxation activity of an aqueous extract of dried immature fruit of Poncirus trifoliata (PF-W) on an isolated strip of rat ileum. Nat Prod Comm 1143- 1148.   (08/2013)
  • dela Peña IC, Yoon SY, Park SJ, Cheong JH. (2013) Effects of ginseol k-g3, an Rg3 enriched fraction, on scopolamine-induced memory impairment and learning deficit in mice. J Ginseng Res 38(1):1-7. (08/2013)
  • dela Peña IC, Jeon SJ, Lee E, Ryu JH, Shin CY, Noh MS, Cheong JH (2013) Neuronal development genes are key elements mediating the reinforcing effects of methamphetamine, amphetamine and methylphenidate. Psychopharmacology (Berl) 230(3):399-413. (08/2013)
  • Park SJ, Jeon SJ, dela Peña IC, Lee HE, Kim DH, Kim JM, Lee YW, Jung JM, Shin BY, Lee S, Cheong JH, Shin CY, Jang DS, Ryu JH (2012). Prunella vulgaris Attenuates Prepulse Inhibition Deficit and Attention Disruption induced by MK-801 in Mice. Phytother Res 27(12):1763-1769.   (08/2012)
  • Kim KC, Kim P, Go HS, Choi CS, Park JH, Kim HJ, Jeon SJ, dela Peña IC, Han SH, Cheong JH, Ryu JH, Shin CY (2012). Male-specific alteration in excitatory post-synaptic development and social interaction in pre-natal valproic acid exposure model of autism spectrum disorder. J Neurochem 124:832-843.   (08/2012)
  • dela Pena JB, Yoon SY, dela Peña IC, Lee HL. dela Pena, IJ. Cheong JH (2012). Pre-exposure to related substances induced place preference and self-administration of the NMDA receptor antagonist-benzodiazepine combination, zoletil. Behav Pharmacol 24(1):20-8. (08/2012)
  • dela Peña JB, Lee HC, dela Peña IC, Woo TS et al. (2012). Rewarding and reinforcing effects of the NMDA receptor antagonist-benzodiazepine combination, zoletil: difference between acute and repeated exposure. Behav Brain Res 232(2):434-442. (08/2012)
  • dela Peña IC, Lee JC, Lee HL, Woo TS, Lee HC, Sohn AR, Cheong JH (2012) Differential behavioral responses of the spontaneously hypertensive rat to methylphenidate and methamphetamine: lack of a rewarding effect of repeated methylphenidate treatment. Neurosci Lett 514(2): 189-193.   (08/2012)
  • dela Peña IC, Yoon SY, Lee JC, dela Pena JB, Sohn AR, Ryu JH, Shin CY, Cheong JH (2012). Methylphenidate treatment in the spontaneously hypertensive rat: Influence on methylphenidate self-administration and reinstatement in comparison with Wistar rats. Psychopharmacology (Berl) 221(2):217-226.   (08/2012)
  • Kim PN, dela Peña IC, Cheong JH, Shin CY (2012). A simple behavioral paradigm to measure impulsive behavior in an animal model of attention deficit hyperactivity disorder (ADHD), the spontaneously hypertensive rats. Biomol Ther 20(1):125-131. (08/2012)
  • Choi JY, Choi YJ, dela Peña, IC, Yoon SY, Lee GS, Shin CY, Ryu JH, Yu GY, Cheong JH (2012). Vitamin C supplementation alleviates electroshock stress but not restraint stress in ICR mice. Food Sci Biotechnol 19:137-144.   (08/2012)
  • Choi JY, dela Peña IC, Yoon SY, Woo TS, Choi YJ, Shin CY, Ryu JH, Lee YS, Yu GY, Cheong JH (2011). Is the anti-stress effect of Vitamin C related with adrenal gland function in rats?. Food Sci Biotech 20(2):429-453. (08/2011)
  • Woo TS, Yoon SY, dela Pena I, Choi JY, Lee HL, Choi YJ, Ryu JH et al. (2011). Anticonvulsant Effect of Artemisia capillaris Herba in Mice. Biomolecules and Therapeutics. 19(3):342-347. (08/2011)
  • dela Peña IC, Ahn HS, Choi JY, Shin CY, Ryu JH, Cheong JH (2011). Methylphenidate self-administration and conditioned place preference in an animal model of attention-deficit hyperactivity disorder: the spontaneously hypertensive rat. Behav Pharmacol 22(1)31-39.   (08/2011)
  • Yoon SY, dela Peña IC, Shin CY, Sohn KH, Lee YS, Ryu JH, Cheong JH, Ko KH (2011). Convulsion-related activities of Scutellaria flavones are related to the 5,7-dihydroxyl structures. Eur J Pharmacol 659:155-60. (08/2011)
  • Ahn HS, dela Peña IC, Kim YC, Cheong JH (2011). 4-Chloro-7-Trifluoromethyl-10H- Benzo[4,5]furo[3,2-b]Indole-1-Carboxylic Acid (TBIC), a Putative BK(Ca) Channel Opener with Uterine Relaxant Activities. Pharmacology 1:87(5-6):331-340.   (08/2011)
  • dela Peña IC, Cheong JH (2011). On benzofuroindole analogues as smooth muscle relaxants. J Biomed Biotech 2011:389056. (08/2011)
  • dela Peña, IC, Ahn HS, Shin CY, Cheong JH (2011). Neuroadaptations involved in long-term exposure to ADHD pharmacotherapies: alterations that support dependence liability of these medications?. Biomol Ther 19(1),9-20. (08/2011)
  • dela Peña IC, Ahn HS, Ryu JH, Shin CY, Park IH, Cheong JH (2011). Conditioned place preference studies with atomoxetine in an animal model of ADHD: Effects of previous atomoxetine treatment. Eur J Pharmacol 667(1-2):238-241.   (08/2011)
  • dela Peña IC, Ahn HS, Choi JY, Shin CY, Ryu JH, Cheong JH. (2010). Reinforcing effects of methamphetamine in an animal model of attention-deficit/hyperactivity disorder-the spontaneously hypertensive rat. Behav Brain Funct 6:72.   (08/2010)
  • dela Peña IC, Yoon SY, Kim SM, Lee GS, Park CS, Kim YC. Cheong JH (2009) Inhibition of intestinal motility by the putative BKCa channel opener LDD175. Arch Pharmacal Res 32:3. (08/2009)
  • dela Peña IC, Yoon SY, Kim SM, Lee GS, Ryu JH, Park C-S, Kim YC, Cheong JH (2009). Bladder-relaxant properties of the novel benzofuroindole analogue LDD175. Pharmacology 83:367-378. (08/2009)
  • Choi JY, dela Peña IC, Choi JH, Yoon SY, Yim DS, Lee YS, Ko KH, Shin CS, Ryu JH, Kim WK, Cheong JH (2008). Psychopharmacological profile of the water extract of Gardenia jasminoides and its constituents, genipin and geniposide, in mice. Biomol Ther 16:2,118. (08/2008)

Books and Chapters

  • dela Peña IC, Bastawrous M, Lozano D, Aguirre D, Hernandez D, Acosta A,  Pabon M, Tajiri N, Kaneko Y, Borlongan CV. (2015) Characterization of the phenotypic features, immuno-modulatory properties and therapeutic potentials of Wharton’s Jelly-derived mesenchymal stromal cells. Cellular Therapy for Stroke and CNS Injuries. J Zhao and J Zhang (Eds.) Springer Series in Translational Stroke Research. Pp.311-334, ISBN 978-3-319-11480-4, DOI: 10.1007/978-3-319-11481-1_14 (08/2015)
  • dela Peña IC, Antoine AA, Reyes S, Hernandez D, Acosta SA, Pabon M, Tajiri N, Kaneko Y, Borlongan CV. (2015) Stem cell-based neuroprotective strategies in stroke.  Neural Stem Cells in Health and Disease. Shetty A (Ed). World Scientific Press, New Jersey. ISBN: 9789814623179. (08/2015)
  • dela Peña, IC, Tajiri N, Acosta SA, Reyes S, Yoo A, McGrogan M, Aizman I, Yankee E, Bates D, Borlongan CV. (2015) From neurogenic niche to site of injury: stem cell-mediated biobridge for brain repair. STEM CELL NICHE- Stem Cell Biology and Regenerative Medicine. Turksen, K (Ed.). Springer International Publishing. Pp. 161-172. ISBN:  978-3-319-21701-7; DOI: 10.1007/978-3-319-21702-4_7. (08/2015)
  • dela Peña JB. Botanas CJ, Tampus R, dela Pena IJ, Kim HJ, dela Pena I*, Cheong JH (2015). Updates on the use of natural treatments for attention-deficit hyperactivity disorder (ADHD), ADHD - New Directions in Diagnosis and Treatment. J Norvilitis (Ed). ISBN 978-953-51-2166-4, Intech Open. pp. DOI: 10.5772/60840. (01/2015)